In this study we have focussed on group 10 allergen of D. pteronyssinus are identified as major allergens and have been well studied 5, 6. More than 20 IgE-binding allergenic components of D. In the tropical and subtropical zones, the major indoor allergens are HDMs, such as Dermatophagoides pteronyssinus ( D. Increasing evidence demonstrates that the sensitization to indoor allergens is a causative factor for the development of airway hypersensitivity 1, 2. Overall, the level of mite or shrimp sIgE is influenced by alterations in age, and vegetarians are at risk of shrimp sensitization via cross-reactivity between shrimp and mite. The mite-Der p 10 not only displayed high cross-reactivity to the shrimp-Pen a 1 in all age groups and vegetarians but functioned as the major allergen to sensitize un-adults. Moreover, adults were more frequently sensitized to shrimp and mite at the same time compared with the un-adult or elderly groups. In contrast, shrimp-induced sIgE was higher in the adults and elderly patients. We found that HDMs induced higher sIgE than shrimp in un-adults. The sera with sIgE levels greater than 3.5 kUA/L were cross-reactivity examined. The serum specific-IgE (sIgE) level of HDMs and shrimp in 60 children/adolescence (un-adults), 30 adults, 30 elderly, and four vegetarian adults patients were measured. Therefore, we assessed the prevalence of shrimp or mite allergy among different age groups and vegetarians. Thus, vegetarians might be sensitized to shrimp through the inadvertent inhalation of HDMs.
Due to the cross-reactivity between shellfish and HDMs, HDMs were considered as the primary sensitizer for shellfish allergy. The sensitization to house dust mites (HDMs) and shrimps affects the development of hypersensitivity with an increase in age.
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